jschembs Posted May 1, 2020 Share Posted May 1, 2020 There's a car company executive who seems to employ a similar strategy. I'd take Musk as president over Trump any day. Oh absolutely, just amusing to me the similarities between the two of them. Both have sociopathic tendencies to a T. Link to comment Share on other sites More sharing options...
jschembs Posted May 1, 2020 Share Posted May 1, 2020 Washington just extended shelter-in-place to May 31st. Link to comment Share on other sites More sharing options...
cwericb Posted May 1, 2020 Share Posted May 1, 2020 On the subject of sociopathic narcissists ... with a very condescending look, Pence delaired that he didn’t need to wear a mask because he tested negative recently. Aside from being disrespectful, aside from setting a poor example, and aside from the fact he could have contracted the virus - or something else - since his test, I believe the tests are only about 85% accurate. So that excuse was about a truthful as his suggestion that he couldn’t look people in the eye with a mask on. His supporters must be so proud. Link to comment Share on other sites More sharing options...
LongHaul Posted May 1, 2020 Share Posted May 1, 2020 "Why are N-95 respirators most often recommended for SARS? The CDC Guidelines for Isolation Precautions in Hospitals recommends that health care workers protect themselves from any disease spread through the air (airborne transmission) by wearing a respirator at least as protective as a fit-tested N-95 respirator.† These guidelines were written before SARS was discovered, but they have been used to protect against other airborne diseases such as tuberculosis." Respirator fact sheet https://www.cdc.gov/niosh/npptl/topics/respirators/factsheets/respsars.html Link to comment Share on other sites More sharing options...
Liberty Posted May 2, 2020 Share Posted May 2, 2020 Oh absolutely, just amusing to me the similarities between the two of them. Both have sociopathic tendencies to a T. I don't think Musk is a sociopath. Possibly Asperger's, if I had to guess, though. Finance people keep trying to read him from the CEO mold/pattern, but he makes a lot more sense if you look at him as the kind of uber-geek that grew up on Slashdot and Ars Technica forums and Hacker News and Reddit humor and trolling, who through sheer force of will and vision ended up a billionaire CEO but was never really of that species, and never took all that seriously, just wants to build cool sci-fi stuff. Obviously the stress and lack of sleep and all that is affecting him. It'd affect anyone under those circumstances.. I wish he'd find better high level people to offload a bunch of stuff (like Shotwell at SpaceX, maybe 3-4 more like her), but delegation doesn't seem his strong suit and ultra-intense, single-minded and brilliant people don't tend to be easy to work with or for up-close... Link to comment Share on other sites More sharing options...
jschembs Posted May 2, 2020 Share Posted May 2, 2020 Oh absolutely, just amusing to me the similarities between the two of them. Both have sociopathic tendencies to a T. I don't think Musk is a sociopath. Possibly Asperger's, if I had to guess, though. Finance people keep trying to read him from the CEO mold/pattern, but he makes a lot more sense if you look at him as the kind of uber-geek that grew up on Slashdot and Ars Technica forums and Hacker News and Reddit humor and trolling, who through sheer force of will and vision ended up a billionaire CEO but was never really of that species, and never took all that seriously, just wants to build cool sci-fi stuff. Obviously the stress and lack of sleep and all that is affecting him. It'd affect anyone under those circumstances.. I wish he'd find better high level people to offload a bunch of stuff (like Shotwell at SpaceX, maybe 3-4 more like her), but delegation doesn't seem his strong suit and ultra-intense, single-minded and brilliant people don't tend to be easy to work with or for up-close... I don't have the time or inclination to find links right now, but I'd argue he exhibits all of these characteristics typically associated with sociopaths. - Lack of empathy - Difficult relationships - Manipulativeness - Deceitfulness - Callousness - Hostility - Irresponsibility - Impulsivity - Risky behavior He's most certainly a genius, but genius often comes with other, less desirable personality traits. Link to comment Share on other sites More sharing options...
DooDiligence Posted May 2, 2020 Share Posted May 2, 2020 Rudy is on Firing Line, right now, with Margaret Hoover. He's coming out of the box like a gigantic, pop-up, douchebag. --- edit: Whoa, now he's flip-flopping & sounding like a normal human being & a thoughtful leader. Who the F is this guy? --- Margaret: What do you think is most important in a leader during this pandemic? Rudy: Truthfulness & discretion. --- This is NOT the Rudy we've been seeing over the past months. --- He just said "trust your doctor, don't trust the president" hastily followed up by "don't trust me, trust your doctor". I predict an orange tinted Tweetstorm. Link to comment Share on other sites More sharing options...
cwericb Posted May 2, 2020 Share Posted May 2, 2020 Thanks, caught the last half of that. I must say he seemed quite reasonable compared to what we have seen over this past winter. "Margaret: What do you think is most important in a leader during this pandemic? Rudy: Truthfulness & discretion." Honest and good answer - but is that not the exact opposite of what we have been seeing? Link to comment Share on other sites More sharing options...
DooDiligence Posted May 2, 2020 Share Posted May 2, 2020 Thanks, caught the last half of that. I must say he seemed quite reasonable compared to what we have seen over this past winter. "Margaret: What do you think is most important in a leader during this pandemic? Rudy: Truthfulness & discretion." Honest and good answer - but is not that is the exact opposite of what we have been seeing? Indeed it is, a good answer, & an about face from what we’ve been seeing. I wonder if Machiavelli was a sociopath? Link to comment Share on other sites More sharing options...
Liberty Posted May 2, 2020 Share Posted May 2, 2020 I don't have the time or inclination to find links right now, but I'd argue he exhibits all of these characteristics typically associated with sociopaths. - Lack of empathy - Difficult relationships - Manipulativeness - Deceitfulness - Callousness - Hostility - Irresponsibility - Impulsivity - Risky behavior He's most certainly a genius, but genius often comes with other, less desirable personality traits. Yeah, I'm not saying there's no possible signs, but the thing is, a lot of non-sociopaths have a lot of these too, right? It's a lot harder to stay balanced under certain stresses and pressures and spotlight (as a lot of regular people who become wealthy/powerful celebrities find out). Maybe he's a very pro-social sociopath, as he seems quite obsessed with old-school science-fiction ideals of saving the world through rationality and ingeniosity. But who knows? Link to comment Share on other sites More sharing options...
jschembs Posted May 2, 2020 Share Posted May 2, 2020 I don't have the time or inclination to find links right now, but I'd argue he exhibits all of these characteristics typically associated with sociopaths. - Lack of empathy - Difficult relationships - Manipulativeness - Deceitfulness - Callousness - Hostility - Irresponsibility - Impulsivity - Risky behavior He's most certainly a genius, but genius often comes with other, less desirable personality traits. Yeah, I'm not saying there's no possible signs, but the thing is, a lot of non-sociopaths have a lot of these too, right? It's a lot harder to stay balanced under certain stresses and pressures and spotlight (as a lot of regular people who become wealthy/powerful celebrities find out). Maybe he's a very pro-social sociopath, as he seems quite obsessed with old-school science-fiction ideals of saving the world through rationality and ingeniosity. But who knows? Right, everything's on a spectrum, and honestly I never even made the connection until I was checking the sociopath boxes vis-a-vis Trump. Elon is way more personable and funny / irreverent than someone like Trump, who is not only a sociopath but also just a horrible human being [not intended to be a political post, as I don't think Trump is even a Republican]. Link to comment Share on other sites More sharing options...
Investor20 Posted May 2, 2020 Share Posted May 2, 2020 So you tell me what criteria you used in picking three out of a lot of European countries to compare? https://en.wikipedia.org/wiki/Scandinavia https://www.worldatlas.com/webimage/countrys/eu.htm You dont mind comparing US with Korea on other side of globe or US with Germany across atlantic but dont want to compare Sweden which is close to UK and Netherlands. New York to Seoul : 6867.74 miles New York to Berlin: 3977 miles Stockholm to Amsterdam: 700 miles https://www.mapdevelopers.com/distance_from_to.php If New york to Seoul or New York to Berlin comparisons are O.K., then Stockholm to Amsterdam comparision is just fine. Link to comment Share on other sites More sharing options...
DocSnowball Posted May 2, 2020 Share Posted May 2, 2020 Sorry haven't been able to keep up with this thread! This is an interesting report on future scenarios: https://www.cidrap.umn.edu/covid-19/covid-19-cidrap-viewpoint "In the first report, published Apr 30, 2020, "The future of the COVID-19 pandemic: lessons learned from pandemic influenza," Kristine Moore, MD, MPH, Marc Lipsitch, DPhil, John Barry, MA, and Michael Osterholm, PhD, MPH, paint a picture of the pandemic and detail how it's behaving more like past influenza pandemics than like any coronavirus has to date. And, because of that, certain inferences can be drawn — such as the fact that it may well last 18 to 24 months, especially given that only 5% to 15% of the U.S. population is likely infected at this point. Key recommendations from the report: States, territories, and tribal health authorities should plan for the worst-case scenario (which involves a large second peak of cases in the fall of 2020), including no vaccine availability or herd immunity. Government agencies and healthcare delivery organizations should develop strategies to ensure adequate protection for healthcare workers when disease incidence surges. Government officials should develop concrete plans, including triggers for reinstituting mitigation measures, for dealing with disease peaks when they occur. Risk communication messaging from government officials should incorporate the concept that this pandemic will not be over soon and that people need to be prepared for possible periodic resurgences of disease over the next 2 years. The first CIDRAP Viewpoint report lays out three scenarios for how cases might ebb and flow in the coming months. No one knows exactly how this virus will behave. But, based on what scientists have recorded so far and on previous influenza pandemics, the report illustrates some of the possibilities." Link to comment Share on other sites More sharing options...
Liberty Posted May 2, 2020 Share Posted May 2, 2020 https://www.cnbc.com/2020/05/01/anthony-fauci-blocked-from-testifying-at-house-coronavirus-hearing.html “ White House blocks Fauci from testifying at House coronavirus hearing” ??? Link to comment Share on other sites More sharing options...
Spekulatius Posted May 2, 2020 Share Posted May 2, 2020 Here is another controversial take. Remdesivir May be worthless. Don‘t have an opinion either way, but it looks the poster may have some valid points. For various reasons (intravenous applications in 10? Doses ) it is unlikely a game changer anyways. https://twitter.com/markhoofnagle/status/1256242036015063042?s=21 Link to comment Share on other sites More sharing options...
Liberty Posted May 2, 2020 Share Posted May 2, 2020 Tomas Pueyo thread on masks and decisions under uncertainty: Also, how someone way over their heads sounds BS’ing their way through everything: Link to comment Share on other sites More sharing options...
Liberty Posted May 2, 2020 Share Posted May 2, 2020 So you tell me what criteria you used in picking three out of a lot of European countries to compare? https://en.wikipedia.org/wiki/Scandinavia https://www.worldatlas.com/webimage/countrys/eu.htm You dont mind comparing US with Korea on other side of globe or US with Germany across atlantic but dont want to compare Sweden which is close to UK and Netherlands. New York to Seoul : 6867.74 miles New York to Berlin: 3977 miles Stockholm to Amsterdam: 700 miles https://www.mapdevelopers.com/distance_from_to.php If New york to Seoul or New York to Berlin comparisons are O.K., then Stockholm to Amsterdam comparision is just fine. No. He said there was a reason to compare to those and you said you didn’t see it. I pointed it out. You can still also compare to everything else including the moon, but Scandinavia is a thing. Link to comment Share on other sites More sharing options...
Peregrine Posted May 2, 2020 Share Posted May 2, 2020 The thing about Sweden...they readily admitted that their death count per capita will be higher than Scandinavian neighbors as a result of their strategy because of a higher rate of infections. But they're also going to see a steeper rise and steeper drop off (like NYC is now). Hard to come to firm conclusions that their deaths per capita will be far worse than their neighbors when it's all said and done. Sweden also has more large nursing homes than other Scandinavian countries and higher population density in its major city, which will figure into the stats as well. Link to comment Share on other sites More sharing options...
ERICOPOLY Posted May 2, 2020 Share Posted May 2, 2020 Pence is just doing his job -- we're not talking about injecting people with disinfectants at present. The man is too bland to be a predictable distraction. But floating rumors about the US defaulting on its debt to China or Remdesivir or whatever... Or... Donald Trump speaks out on bombshell UFO Pentagon footage https://www.express.co.uk/news/world/1276235/Donald-Trump-pentagon-UFO-video-alien-footage Link to comment Share on other sites More sharing options...
DocSnowball Posted May 2, 2020 Share Posted May 2, 2020 Here is another controversial take. Remdesivir May be worthless. Don‘t have an opinion either way, but it looks the poster may have some valid points. For various reasons (intravenous applications in 10? Doses ) it is unlikely a game changer anyways. https://twitter.com/markhoofnagle/status/1256242036015063042?s=21 3 trial results came out the same day: NIH ACTT trial - discharge in 11 days vs 15, mortality 8% vs 11.6% in Remdesivir vs control arms ( so reduced morbidity, second order effects on reducing overburdened health care systems) https://www.niaid.nih.gov/news-events/nih-clinical-trial-shows-remdesivir-accelerates-recovery-advanced-covid-19 SIMPLE trial - 5 days and 10 days use showed no significant differences (so can be used in shorter course). IDK why they did not release any data about the control arm in this one, I thought it had it... https://www.gilead.com/news-and-press/press-room/press-releases/2020/4/gilead-announces-results-from-phase-3-trial-of-investigational-antiviral-remdesivir-in-patients-with-severe-covid-19 China Remdesivir trial 237 patients data - no significant mortality benefit https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31022-9/fulltext As far as the twitter poster goes, one point well taken is that the next population to study in trials would be earlier start of treatment (now that we have same day per testing) and high risk non-hospitalized patients (somehow delivering at home maybe). Sarilumab phase 2 data also came out, with phase 2 outcome met and phase 3 trial focusing on critically ill patients only where potential to reduce mortality is being seen. Thirdly a lot of attention is going towards the prothrombotic effects of the virus as well as proning early. Stacking all of them and what we know about the virus after all this time, I think mortality will be lower in the future, although a little bit lower not a lot lower (just my opinion). Link to comment Share on other sites More sharing options...
Spekulatius Posted May 2, 2020 Share Posted May 2, 2020 Here is another controversial take. Remdesivir May be worthless. Don‘t have an opinion either way, but it looks the poster may have some valid points. For various reasons (intravenous applications in 10? Doses ) it is unlikely a game changer anyways. https://twitter.com/markhoofnagle/status/1256242036015063042?s=21 3 trial results came out the same day: NIH ACTT trial - discharge in 11 days vs 15, mortality 8% vs 11.6% in Remdesivir vs control arms ( so reduced morbidity, second order effects on reducing overburdened health care systems) https://www.niaid.nih.gov/news-events/nih-clinical-trial-shows-remdesivir-accelerates-recovery-advanced-covid-19 SIMPLE trial - 5 days and 10 days use showed no significant differences (so can be used in shorter course). IDK why they did not release any data about the control arm in this one, I thought it had it... https://www.gilead.com/news-and-press/press-room/press-releases/2020/4/gilead-announces-results-from-phase-3-trial-of-investigational-antiviral-remdesivir-in-patients-with-severe-covid-19 China Remdesivir trial 237 patients data - no significant mortality benefit https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31022-9/fulltext As far as the twitter poster goes, one point well taken is that the next population to study in trials would be earlier start of treatment (now that we have same day per testing) and high risk non-hospitalized patients (somehow delivering at home maybe). Sarilumab phase 2 data also came out, with phase 2 outcome met and phase 3 trial focusing on critically ill patients only where potential to reduce mortality is being seen. Thirdly a lot of attention is going towards the prothrombotic effects of the virus as well as proning early. Stacking all of them and what we know about the virus after all this time, I think mortality will be lower in the future, although a little bit lower not a lot lower (just my opinion). Thanks for the comments. I agree that treatment is improving (and has already) and mortality will be lower. Even though we go down the path of herd immunity , I think there is a huge benefit of getting the perhaps inevitable infection later rather than sooner. Link to comment Share on other sites More sharing options...
Dalal.Holdings Posted May 2, 2020 Share Posted May 2, 2020 Here is another controversial take. Remdesivir May be worthless. Don‘t have an opinion either way, but it looks the poster may have some valid points. For various reasons (intravenous applications in 10? Doses ) it is unlikely a game changer anyways. https://twitter.com/markhoofnagle/status/1256242036015063042?s=21 3 trial results came out the same day: NIH ACTT trial - discharge in 11 days vs 15, mortality 8% vs 11.6% in Remdesivir vs control arms ( so reduced morbidity, second order effects on reducing overburdened health care systems) https://www.niaid.nih.gov/news-events/nih-clinical-trial-shows-remdesivir-accelerates-recovery-advanced-covid-19 SIMPLE trial - 5 days and 10 days use showed no significant differences (so can be used in shorter course). IDK why they did not release any data about the control arm in this one, I thought it had it... https://www.gilead.com/news-and-press/press-room/press-releases/2020/4/gilead-announces-results-from-phase-3-trial-of-investigational-antiviral-remdesivir-in-patients-with-severe-covid-19 China Remdesivir trial 237 patients data - no significant mortality benefit https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31022-9/fulltext As far as the twitter poster goes, one point well taken is that the next population to study in trials would be earlier start of treatment (now that we have same day per testing) and high risk non-hospitalized patients (somehow delivering at home maybe). Sarilumab phase 2 data also came out, with phase 2 outcome met and phase 3 trial focusing on critically ill patients only where potential to reduce mortality is being seen. Thirdly a lot of attention is going towards the prothrombotic effects of the virus as well as proning early. Stacking all of them and what we know about the virus after all this time, I think mortality will be lower in the future, although a little bit lower not a lot lower (just my opinion). The problem with early therapy using Remdesivir is that it's very hard to manufacture. If you are opening up Remdesivir to not just severe cases, but mild/moderate and earlier stages in infection when symptoms are not that bad, that potentially opens up millions of potential patients as candidates for therapy. As we know, ~80% of people don't get to severe. You would now be treating a lot of those 80% with the drug instead of reserving it to just the severe patient group (because you have little idea which patients will end up with severe manifestations and which ones will not early in the course of covid). Meanwhile, Gilead is only going to have achieved 140,000 courses manufactured by the end of May. They are hoping for ~1 million # of courses manufactured by end of yr I believe... https://www.wsj.com/articles/gilead-to-expand-manufacturing-of-covid-19-drug-remdesivir-11588281598 Link to comment Share on other sites More sharing options...
Liberty Posted May 2, 2020 Share Posted May 2, 2020 Pence is just doing his job -- we're not talking about injecting people with disinfectants at present. The man is too bland to be a predictable distraction. But floating rumors about the US defaulting on its debt to China or Remdesivir or whatever... Or... Donald Trump speaks out on bombshell UFO Pentagon footage https://www.express.co.uk/news/world/1276235/Donald-Trump-pentagon-UFO-video-alien-footage How could I forget that one. And wasn’t Kudlow talking about the China trade deal (phase 1, ha!) too? Anything to change focus... Remember when they teased that one every other day like it was Groundhog Day last year? Link to comment Share on other sites More sharing options...
Liberty Posted May 2, 2020 Share Posted May 2, 2020 Skeptical take on intubation: https://www.spectator.co.uk/article/ventilators-doctor-movement Link to comment Share on other sites More sharing options...
Dalal.Holdings Posted May 2, 2020 Share Posted May 2, 2020 Singapore continues to have exceptionally low mortality (1/1000 of confirmed cases). This could be due to: 1) Recent rise in infections (deaths could surge in the coming weeks) 2) Aggressive testing (leading to large # of confirmed cases), contact tracing (limiting spread to vulnerable groups) Or, more optimistically: 3) Protection in the host in humid/warm (tropical) climates due to factors such as enhanced innate immune protection of lung--which has been shown with Influenza: https://www.pnas.org/content/116/22/10905 If #3 is true, one would hope for a drop in mortality during the summer months in the Northern Hemisphere. Also if true, perhaps this would be the ideal time to catch it and (hopefully) develop immunity. This is all speculation at this point. Link to comment Share on other sites More sharing options...
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