GLP-1 disruption

[John Hjorth]

Thank you, @nsx5200 and @Fly,

 

Now we're actually getting somewhere, I think.

 

'The bad guys' [from general sentiment] named 'culprits',so far, has been the Pharmacy Benefit Managers [PBMs] and the producers [because of their profits by doing so], while the roots to the issue at hand is far reaching to a wider extent, rooted into culture and way of living.

 

Basically it boils down to taking responsibility for own body, dosen't it?

Edited August 20 by John Hjorth
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[nsx5200]

11 hours ago, John Hjorth said:

Basically it boils down to taking responsibility for own body, dosen't it?

That's a very simplistic way of looking at it.  Environment and incentives has a way of influencing personal decisions as well.  Who doesn't want to be as healthy as possible, and if so, what's stopping them?  Economic incentives has a strange way of distorting personal actions.

 

If we invert the problem such that we try to get the worst health outcome possible, what kind of food would we advocate, and what kind of activities would we recommend?

[rogermunibond]

Critics like Michael Pollan have condemned the agro-industrial-food complex but I think the impetus for the US govt's involvement back in the 1920-30 period was to prevent the creep of socialism and civil unrest.  This was extended even further in the 70s under Nixon.  The goal was to make certain cash crop production stable and increasing to keep a lid on food cost inflation.  The policy probably performed too well.

[fareastwarriors]

It does it all?

 

 

Eli Lilly’s weight loss drug slashes the risk of developing diabetes in long-term trial

 

Eli Lilly’s weight loss drug reduced the risk of developing Type 2 diabetes by 94% in obese or overweight adults with pre-diabetes compared to a placebo, according to initial results from a long-term study.

 

 

[UK]

https://www.economist.com/briefing/2024/10/24/glp-1s-like-ozempic-are-among-the-most-important-drug-breakthroughs-ever

[Spekulatius]

1 hour ago, UK said:

https://www.economist.com/briefing/2024/10/24/glp-1s-like-ozempic-are-among-the-most-important-drug-breakthroughs-ever

Here is the non paywall (at least for some) version:

https://archive.ph/p2YaA

 

These GLP-1 drugs really seems like a miracle to me. The ancillary effects seem powerful and compound in a positive way. Most of the time, you have positive and negative “side” effects but in this case, it seems like a lollapalooza of positive side effects.

 

I think far more people should take them. 

[John Hjorth]

This may overlap to other areas of science in general, so not only related what's going on in the pharma industry related to GLP-1 [but let's keep it here related to GLP-1] :

 

Does any of my fellow CoBF members have any concerns and / or qualifications related to this scientific method running science alone based empirical and statistical evidence, making science 'powerfull' as a basis only by using giant samples [, because 'big pharma' has the access to the means to do so'], with the normative side of things, with regard to recognition and knowledge, running, not following similar suit, thereby leaving the question 'Why does it work?' unanswered, perhaps not even paid any really attention to?

 

- - - o 0 o - - -

 

Just mentioning it here : Isen't that also what AI is about? [Like : Several thousands years of evolved Chineese medicine working, without even anybody really knowing why ...]

Edited October 27 by John Hjorth