Vish_ram

FDA finally approved Afrezza

Thanks for the links Onyx1. I just found out that Tim Howard was the ex-CFO of Fannie Mae. I ordered his book on amazon now. http://www.amazon.com/Mortgage-Wars-Big-Money-Politics-Collapse-ebook/dp/B00GJNTO4U/ref=sr_sp-atf_title_1_1?ie=UTF8&qid=1403712820&sr=8-1&keywords=tim+howard+fannie+mae

The author is incorrect; http://research.stlouisfed.org/fred2/graph/fredgraph.png?g=E1d Check out the graph above where I'm showing both the CPI's. Both have fallen. The reason for less steeper fall in housing is due to the stickiness on way down (people freeze up and sell less when prices are down, the volume drops a lot). In the longer term, they play catch up most of the time.

To those that follow macro indicators, what indicators that you track can foretell a recession? I find yield curve inversion, employees in residential construction, negative growth in employees working in trucking/transportation etc to be good indicators.

http://money.cnn.com/2014/06/07/investing/stock-market-trading-oracle-ohio/index.html?iid=HP_LN How did he predict the 07 recession?

For many investors, a market returns with lower volatility (of the negative variety) is a big deal.

http://seekingalpha.com/article/2243613-make-70-percent-a-year-with-math I don't know why Harry Long looks pissed. Wont you be happy with this kind of returns?

Does anyone know if a US based RIA can manage assets for a canadian investor? Does Canada require any registration?

For helping me realize that you don't need money to be happy.

Forget investing, any lawful action is good for the society. Anyone having any interaction with society in lawful ways is good for the society. Next comes the Q, who is doing more good? Is Buffett doing more good than Buffett's barber? A big portion of Buffett's good should be attributed to his family, barber, professors, college, cops/firefighters in Omaha, tailor etc ..... Buffett used all the social capital that he could get.

click on poster name and then click on "show posts"

The value of the call option gets reduced by the amount of the dividend. Nestle pays a high div. I don't understand how this works. Do you have articles you can refer me to? http://www.putcallparity.net/put-call-parity-of-european-options-with-dividends call = stock + put - dividend - X (capital needed to exercise the option, adj for rates)

The value of the call option gets reduced by the amount of the dividend. Nestle pays a high div.

Total return fund reminds me of Fidelity Magellan fund in late 90s.

1) your guess is as good as anybody else's 2) the indices are maintained by a company/group of people. it is on paper and they can add or remove with gay abandon. The funds (ETF's) that track the indices should buy/sell to track the index (reduce tracking error). When they do it, they'll incur capital gains that are passed to shareholders.

The fed was also confused. you had high inflation due to oil shock, fed increased rates. Then economy tanked, Fed dropped the rates. All this happened in a span of 1-2 years.

Ruhle should change her last name to "Rude"

Eric Your act of taking margin debt to buy BAC common (buying puts to hedge it) is no different than what a bank does, am I right? A bank is short near term and long the deep end of curve and profits when yield curve is upward sloping. You are like a bank that is betting on a bank. This works great as long as fed is accommodative. When yield curve inverts, will you close down the margin debt? your margin debt if tied to fed funds will keep going up and total costs (margin interest+ diminishing put premiums) may not exceed the returns on BAC.

Some might question that this is not value investing. Nevertheless, I would like to know the econ charts that you watch to gauge the economic activity, market valuations etc. Please provide the source of the chart/graph. I run some charts in St Louis fed data for GDP/market cap Tobin's Q, S&P 500 vs fed funds rate etc

I really wonder what his money weighted returns are. We know his time weighted returns starting inception. if he had 40-50% returns in initial years and lousy ones later one, then very few benefited from his returns that he is claiming. He really had some half a dozen stocks that lost more than 99%, and with permanent capital losses. some examples are cryptologic, delta financial, pncl, compucredit, TMM etc. Some others like HNR he lost 50+%. Kudos to him for bouncing back. Some lesser mortals would have been psychologically devastated.

I like the concept of legalizing pot. The challenge is how do we get it off kids? The money, untaxed that is siphoned off to columbia and other countries is halted. the illegal drug trade kills people on both side of borders, fills up our prison, cops spend time and money to control the uncontrollable. We legalize and tax it just like tobacco.

Pot stocks are on fire http://money.cnn.com/2014/01/07/investing/marijuana-stocks/index.html?hpt=hp_t2

I can make an argument that market is very cheap based on market cap/GDP. The GDP/GNP are practically same. 1) Someone (pupil I think) earlier had mentioned the profits generated by US companies in non-US soil. This reflects in market cap but not in GDP or GNP (as GNP only includes earnings by US person in foreign soil). 2) The corporate profits as a percentage of gdp historically is 6.2, right now it is more than 11%. Lets not go into details as to why it is high or will it mean revert. The profits drive market capitalizations. So all things equal, we can afford to have say 25% higher market cap due to superior profits. http://research.stlouisfed.org/fred2/graph/?g=cSh If we apply both these factors and normalize it, we may be closer to the average market cap/GDP ratio of 60%. Far from the bubble territory.

no_free_lunch You are right that the long term effect of inhaled insulin on lungs is unknown. Afrezza has been used in one shape or form for last 10+ years. No matter how good the product is, a good portion of patients will be turned off by this issue. I had an email conversation with Dr Kayed year or two back ----------------------------------- From: "Kayed, Rakez" < Sent: Sun, August 15, 2010 11:37:15 AM Subject: RE: amyloid aggregates article Short answer; I do not know how it will affect other insulin inhalers, since we did not test them, and we do not know what happens in humans, since we did not have access to tissues from the lungs of humans who used the inhalers. Our research focus is amyloid formation not drugs evaluation, in this study we were investigating protein aggregation at the interface, after our initial discovery that inhaled insulin forms amyloid in the lung, we performed many experiment in vitro, and we were surprised how poor the quality of the insulin encapsulated in these kits was. Its aggregation kinetics was worst that the recombinant insulin we bought in bulk. Still we hope our novel findings will insure that scientists and companies look more carefully at insulin aggregation both in vitro and in vivo. We did not have access human tissues from people who used the inhalers. This is the first report describing these novel findings,thus we are sure that many researchers especially those who have access to human tissue will look at this phenomena in humans (remember humans are different than mice). Also we are confident that they will look more carefully at the quality of the insulin intended for human use to insure higher quality. Also we were not able to test the clearance of amyloid in the lungs after discontinuing the treatment, because we did not have enough inhaled insulin to complete these experiments (Exubera was withdrawn from the market) we tried to obtain more kits by contacting Pfizer and Necktar directly with no success, still be believe that in mice the effects are irreversible because we found caspase activation. Best Regards rakez Rakez Kayed, PhD Assistant Professor Department of Neurology George and Cynthia Mitchell Center for Neurodegenerative Diseases ----------------------------------------- My email read your article "Inhaled Insulin Forms Toxic Pulmonary Amyloid Aggregates" with lot of interest. I'm not in research, but I'm a shareholder of Mannkind corporation. I'm trying to understand how your findings impact Mannkind's Afrezza. As you may know, Afrezza is a proprietary FDKP with monomeric insulin. It is inhaled similar to Exubera. Both are different compounds. 1) Do you think inhaling afrezza will also cause amyloid aggregates? 2) In your study, the rats were subjected to Exubera for 7 days only, in Exubera trials patients were exposed for years and after the initial drop in FEV/PFT measurements, there was a non-progressive reversible decline in lung function. Why do you think in Exubera trials, over the years the amyloids didn't aggregate on and on and cause a continuous lung function decline? I would really appreciate your feedback ---------------------------------------------------------------------------------- I've some more info on it from other knowledgeable posters. email me in private if you are interested I've a small (speculative) position.

Place a 1 cent ask (sell ) in your account. IF you have a retirement account (non-taxable), then place a buy at same 1 cent. You are paying yourself, but taking the loss on taxable account. You only pay the trading costs in both accounts. Allow the puts to expire in retirement account