Me too. I read the book and I have been following his podcast since it started. I found the book a nice summary if person doesn't want to listen to the many hours of the podcasts.
My takeaways are:
the finer details of diets are probably less important than we realize. For example, paleo vs keto vs vegan etc... Stick with real food (meat, vegetables, fruits, etc). More importantly, stay away from highly processed food, added sugars.
insulin sensitivity is super-important. Type 2 Diabetes and insulin insensitivity is a gateway to other diseases.. heart disease, cancer, Alzheimer's (although of course there are no guarantees)
Because insulin sensitivity is super important, maintaining muscle mass through your life is also really important, which leads to the next point
exercise is also super important. Both cardio fitness and maintaining muscle mass through resistance training
Attia's editorial on the current medical system is spot on in my opinion. There is not nearly enough done for preventative care. Health care is really sick care. Once you you have heart disease, it is really hard to restore you back to your original healthy self. It's much better to do testing (eg early extensive lipids tests) and interventions when a person is in their 20s, 30s, and 40s, rather than waiting until they are 70 and their arteries are totally clogged.