Investor20

It can be true because in real terms wages and investments are down this year From October 2021 to October 2022a 2.9-percent decrease in real average weekly earnings over this period Real Earnings News Release - 2022 M10 Results (bls.gov) https://www.reuters.com/markets/europe/global-markets-flows-urgent-2022-10-14/ "60/40" portfolios are facing worst returns in 100 years: BofA" Global Wage Report: Rising inflation brings striking fall in real wages, ILO report finds estimates that global monthly wages fell in real terms to minus 0.9 per cent in the first half of 2022 – the first time this century that real global wage growth has been negative. From Real (inflation adjusted) Annualized S&P 500 Return (Dividends Reinvested): -20.048% for 2022 (screen shot attached) Warren Buffet on inflation: Inflation swindles almost everybody. To me a big drop in investments and negative wages is a recession...whatever official definition may be and we are already in one.

The problem is the excess mortality today for younger people is more than in 2020. 2020 has least excess deaths of 2020, 2021 and 2022. Below data given for 0-24 for similar trend for 24-44 years too. From USmortality.com For 0-24 year olds: United States reported 64,467 deaths, for the 52 weeks of year 2020 (0-24 years of age). Expected deaths were 60,263. That is an increase of +4,204 deaths (+7.0%). United States reported 68,264 deaths for the 52 weeks of year 2021 (0-24 years of age). Expected deaths were 59,022. That is an increase of +9,242 deaths (+15.7%). Year to date, United States reported 56,075 deaths for the 45 weeks of year 2022 (0-24 years of age). Expected deaths were 50,429. That is an increase of +5,646 deaths (+11.2%).

"From Sept. 1, public buildings - with the exception of social institutions like hospitals - are to be heated to a maximum 19 degrees Celsius, and the heating could be turned off entirely in corridors and foyers." Emphasis in bold added https://www.reuters.com/business/energy/german-government-approves-energy-saving-measures-rein-gas-usage-2022-08-24/

From August 2021 to August 2022, .... resulted in a 3.2-percent decrease in real average weekly earnings over this period. https://www.bls.gov/news.release/realer.htm There is no Pay Increase. The workers are only asking for raises to keep up with inflation for their ends to meet. Emphasis in bold added

I am not clear why many here feel job market is strong. Just because people are asking for a raise in high inflationary situation doesn't mean the job market is strong. It could as well mean they cannot have ends meet with present income. Looking at real weekly earnings (inflation adjusted) there is a steady drop of median from Q2 2020 at 393 to present 358$. That is a whopping 8.9% real earnings drop in last two years. https://fred.stlouisfed.org/series/LES1252881600Q# If you were to look at civilian labor force participation, it was at 63.4% in Feb 2020 to present 62.4%. That is a loss of 1%, or over 3 milion employees lost. Loss of 3 million employees lost from pre-Covid (Jan 2020) and negative 8.9% median real wages hardly show a strong job market. If people want a raise, it only means their expenses went up and need more to have their ends meet. https://www.bls.gov/charts/employment-situation/civilian-labor-force-participation-rate.htm

I am not sure why this is moved to General Discussion. This is an investment idea in a start up company. Investments in start ups are different in process and one has to be accredited investor. Yet this is investment idea than General discussion. Please move it back to investment forum. Thanks

I have an investment in Novuson surgical. Their website is http://novuson.com The short story is that traditional cauterization techniques are electricity and heat based that cause smoke and charring. Novuson is developing Ultrasound based Cauterization and in the process of doing testing for FDA filing. Please see two videos that show the technology. From their PR "Novuson Surgical's patented technology delivers Direct Therapeutic Ultrasound (DTU) energy for cauterization and hemostatic control without transmission of electricity through the patient, and provides safety and predictability in the most critical surgical applications." My investment was based on my discussion with a few surgeons who did say the traditional cauterization do have problems such as referred smoke and charring. Additionally, as per CDC smoke plume during surgery is a problem and smoke should be minimized. https://www.cdc.gov/niosh/topics/healthcarehsps/smoke.html Surgical smoke is produced by the thermal destruction of tissue by use of lasers or electrosurgical devices. Not only is surgical smoke a nuisance because it has a repulsive odor and can obstruct the surgeon’s view of the surgical site,..... Acute health effects of exposure to surgical smoke include: Eye, nose and throat irritation Headache Cough Nasal congestion Asthma and asthma-like symptom CDC recommends minimizing such surgical smoke. I believe this is a huge advantage for this technology, because once it is approved, this could be a driver to have hospitals switch to smoke less cauterization. The terms they gave for a convertible note " (i) Notes will convert at a pre-money valuation equal to the lesser of (i) 80% of the pre-money valuation of such offering, or (ii) $11,800,000. I am only an investor at Novuson and if you want more details, I can get you to talk to their CEO. If there is sufficient interest from enough people, they could do a webinar. Below are two videos of their technology. Videos of technology: https://app.box.com/s/y1ij7j2ip9mkkx3i001u5bahaif0xjqc https://app.box.com/s/affknz9e5hl30fpfjol87kv1c7b19j7r

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00160-0/fulltext April 09, 2021 Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial "....indicating a relative risk reduction of 91% for budesonide." Interpretation Early administration of inhaled budesonide reduced the likelihood of needing urgent medical care and reduced time to recovery after early COVID-19. Note: Please consult a physician for any treatment. Any medication has contraindications. Only for discussion.

This article had selective citations. I have written before about Hydroxychloroquine and Ivermectin. But let us look at Convalescent plasma. https://www.nejm.org/doi/full/10.1056/NEJMoa2033700 Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults Conclusions Early administration of high-titer convalescent plasma against SARS-CoV-2 to mildly ill infected older adults reduced the progression of Covid-19. https://www.nejm.org/doi/full/10.1056/nejmoa2031304 A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia Conclusions No significant differences were observed in clinical status or overall mortality between patients treated with convalescent plasma and those who received placebo. ......... So medicines work better when patient is treated early...hardly a noble laureate level finding.

One area that has shown potential for reduced transmission is Ivermectin. If you look at the meta-analysis of four RCTs with Ivermectin in below link (Page 14), they have Moderate certainty evidence suggests that ivermectin prophylaxis among health care workers and COVID-19 contacts probably reduces the risk of COVID-19 infection by about 88% (4 studies, 851 participants; RR 0.12, 95% CI 0.08 to 0.18; 4.3% vs 34.5% contracted COVID-19). https://b3d2650e-e929-4448-a527-4eeb59304c7f.filesusr.com/ugd/593c4f_1b1399cb64514dc4bdcbef0cd15f7878.pdf 88% reduction is more than 50% given by AstraZeneca. However, the push back is these are not well done studies and are not large studies. Ofcourse no one does large studies as Ivermectin is so cheap, it is practically free. There is also one more study not included in the above meta-analysis: AIIMS find ivermectin prophylaxis reduces infection in Covid-19 patients https://www.pharmaceutical-technology.com/news/aiims-study-covid-19/ A study by All India Institutes of Medical Sciences (AIIMS)-Bhubaneswar in the Indian state of Odisha found that two doses of potential drug ivermectin prophylaxis resulted in a 73% reduction in Covid-19 infection. Note: Only for discussion. Not a suggestion to take any medication. Please follow your physicians advise.

The real question is can vaccines take us to herd immunity. There are doubts about that. Please read below article: Five reasons why COVID herd immunity is probably impossible https://www.nature.com/articles/d41586-021-00728-2 The key to herd immunity is that, even if a person becomes infected, there are too few susceptible hosts around to maintain transmission — those who have been vaccinated or have already had the infection cannot contract and spread the virus. The COVID-19 vaccines developed by Moderna and Pfizer–BioNTech, for example, are extremely effective at preventing symptomatic disease, but it is still unclear whether they protect people from becoming infected, or from spreading the virus to others. That poses a problem for herd immunity. “Herd immunity is only relevant if we have a transmission-blocking vaccine. If we don’t, then the only way to get herd immunity in the population is to give everyone the vaccine,” says Shweta Bansal, a mathematical biologist at Georgetown University in Washington DC Even though the discussion is about Pfizer and Moderna which they are starting studies of infection and transmission, AstraZeneca released some data about infection. In below study they showed... "The data showed that PCR positive readings were reduced by 67% (CI: 49%, 78%) after a single dose, and 50% (CI: 38% to 59%) after the two dose regimen, supporting a substantial impact on transmission of the virus." https://covid19.astrazeneca.com/latest-news/primary-analysis-trial-data.html It could be as low as 38%, which considering mutations and reduction in mitigation such as distancing could cancel out. I am being fair, waiting for full data to make a judgement.

But they are not claiming that with this vaccine - atleast not yet. Read the Fauci comments given in the link. They are claiming even if someone gets infected after vaccination, they will get less symptoms. But that person could still transmit to others. Whether they get less infected and less transmission after vaccination is still being studied. Making unproven claims will make people question genuine claims.

If you get vaccinated, it helps you is the claim for vaccine. But even Fauci is not saying it helps others. It is far easier to convince people to take a vaccine because its good for them rather than make up that it reduces transmission to others which is still being studied and raises suspicions about other claims of vaccine.

https://www.webmd.com/vaccines/covid-19-vaccine/news/20210326/covid-vaccine-spread-study March 26, 2021 "Fauci: Study Will Tell if COVID Vaccine Stops Spread" “We hope that within the next 5 or so months, we’ll be able answer the very important question about whether vaccinated people get infected asymptomatically,” he said, “and if they do, do they transmit the infection to others.” Why do they ask fully vaccinated people to wear masks. Socially distance. My friend in NY westchester county who is fully vaccinated was asked for a one week quarantine and PCR test to have some tests done at a hospital. Now, clarifying this information, why do you think it matters to you whether others are vaccinated as long as you are vaccinated?

Explain to me how you taking vaccine helps others? Is it not easier always to convince people it is in their interest - in this case to take the vaccine than these statements? Would it be not more polite to just say, I got vaccine...I am protected.